Peer-Reviewed Studies
Journal of Medicinal Food, Volume 5, Issue Number 1, 2002. Antioxidant Capability and Efficacy of Mega-H?? Silica Hydride, an Antioxidant Dietary Supplement, by in Vitro Cellular Analysis Using Photosensitization and Fluorescence Detection.
The Abstract summarizes that the silica hydride is “an effective method of reducing free radical activity by more than 96% against a singlet oxygen species and more than 86% for hydroxyl and superoxide free radicals.” The study notes that the silica hydride has “demonstrated in vitro reducing abilities, as measured by ORP. Additionally, it creates a slightly alkaline microenvironment with a relative hydrogen pressure (rH) value thousands of times greater than that of other tested antioxidants.” The study also points out that “most marketed antioxidants actually create an acidic or neutrally buffered environment. Cumulatively, silica hydride has many positive attributes as an effective antioxidant.”
International Journal of Hydrogen Energy, Volume 29, Issue 11, 2003. Synthesis of a Novel Anionic Hydride Organosiloxane Presenting Biochemical Properties.
The compound “will reduce the ORP reading to -750 mV for a period of at least several weeks. Most antioxidant compounds are relatively large chemical species. Examples of this are vitamin A, K, C, ubiquinone and n-acetyl-cystine.” “Particular uses include nutritional supplementation as an antioxidant. The incredible reduction potential of silica hydride adds to the possible uses of this type of compound.” This study also referred to a recent publication of a clinical study that “illustrated the capability of this compound to significantly reduce lactic acid after exercise by 50%.” The study concludes that “this nanosized colloidal bioencapsulated compound could be an incredibly effective radical scavenger and aid in the reduction of oxidative stress due to its minimal size and high reduction potential.”
Free Radical Biology and Medicine, Volume 35, Issue 9, 2003. Antioxidant Capacity of Silica Hydride: A Combination Photosensitization and Fluorescence Detection Essay.
The abstract notes that the analysis “resulted in an easy and effective method for quantifying reactive oxygen species reduction and characterized the radical reduction efficacy of silica hydride at 97% against singlet oxygen species and over 87% for the combination of hydroxyl and superoxide reactive species, and 98% effective for hydroxyl radical species. Nontreated photosensitized controls showed less than 1% viability under the same conditions.” The study concludes by stating that “this article proposes that the use of silica hydride may significantly reduce the oxidative stress and resultant pathologies induced by ROS in an efficient and effective manner.”
International Journal of Hydrogen Energy, Volume 29, Issue 5, 2004. Non-toxic Hydride Energy Source for Biochemical and Industrial Venues: ORP and NAD+ reduction analyses.
The study finds out from its analysis that silica hydride demonstrates the compound as a significant reducing agent and potential energy source. “From the biological standpoint, the silica hydride compound has considerable additional properties, as a reducing agent for free radicals in the body and as an internal, cellular fuel cell.” Tests results “indicate no induced cellular toxicity from the silica hydride or the resultant increased NADH concentration. Combinatorially, the low ORP, reduced rH, and ability to consistently reduce NAD provide a solid basis for further investigation into this hydride family as an alternate hydrogen mechanism in biological and industrial arenas.”
Journal of Medicinal Food, Volume 7, Issue Number 1, 2004. Differential Metabolic Effects on Mitochondria by Silica Hydride Using Capillary Electrophoresis.
“The results of this assay indicate an increase in metabolic rate and internal cellular energy production relative to the nontreated system.” “In the mitochondrial samples, the ratio of NADH/NAD increased twofold, the ATP increased fivefold and glucose levels decreased twofold.
” A controlled clinical trial showed that in eight normal adult subjects, seven of the nine Biological Terrain Assessment parameters improved. Saliva pH, saliva rH2, blood resistivity, and urine resistivity showed statistically significant improvement (p >0.05) for these eight subjects after 18 days of supplementation with 4 Microhydrin (now known as Active H-) capsules per day on a schedule of one in the morning, two at midday and one in the evening. Three other parameters (urine pH, urine rH2, and saliva resistivity) also showed improvement over the 18-day supplementation period when their averaged changes were calculated. Blood pH and blood rH2 were the only parameters that did not change during the supplementation period. These values may not change as readily due to the heterogenous and stable nature of blood. The nutritionists and physicians who monitored the study with Biological Terrain Assessment results and other clinical data observed no adverse side effects in this group during the supplementation period. Presented at the American College of Nutrition Symposium on Advances in Clinical Nutrition. Albuquerque, New Mexico, October, 1998.
The Abstract summarizes that the silica hydride is “an effective method of reducing free radical activity by more than 96% against a singlet oxygen species and more than 86% for hydroxyl and superoxide free radicals.” The study notes that the silica hydride has “demonstrated in vitro reducing abilities, as measured by ORP. Additionally, it creates a slightly alkaline microenvironment with a relative hydrogen pressure (rH) value thousands of times greater than that of other tested antioxidants.” The study also points out that “most marketed antioxidants actually create an acidic or neutrally buffered environment. Cumulatively, silica hydride has many positive attributes as an effective antioxidant.”
International Journal of Hydrogen Energy, Volume 29, Issue 11, 2003. Synthesis of a Novel Anionic Hydride Organosiloxane Presenting Biochemical Properties.
The compound “will reduce the ORP reading to -750 mV for a period of at least several weeks. Most antioxidant compounds are relatively large chemical species. Examples of this are vitamin A, K, C, ubiquinone and n-acetyl-cystine.” “Particular uses include nutritional supplementation as an antioxidant. The incredible reduction potential of silica hydride adds to the possible uses of this type of compound.” This study also referred to a recent publication of a clinical study that “illustrated the capability of this compound to significantly reduce lactic acid after exercise by 50%.” The study concludes that “this nanosized colloidal bioencapsulated compound could be an incredibly effective radical scavenger and aid in the reduction of oxidative stress due to its minimal size and high reduction potential.”
Free Radical Biology and Medicine, Volume 35, Issue 9, 2003. Antioxidant Capacity of Silica Hydride: A Combination Photosensitization and Fluorescence Detection Essay.
The abstract notes that the analysis “resulted in an easy and effective method for quantifying reactive oxygen species reduction and characterized the radical reduction efficacy of silica hydride at 97% against singlet oxygen species and over 87% for the combination of hydroxyl and superoxide reactive species, and 98% effective for hydroxyl radical species. Nontreated photosensitized controls showed less than 1% viability under the same conditions.” The study concludes by stating that “this article proposes that the use of silica hydride may significantly reduce the oxidative stress and resultant pathologies induced by ROS in an efficient and effective manner.”
International Journal of Hydrogen Energy, Volume 29, Issue 5, 2004. Non-toxic Hydride Energy Source for Biochemical and Industrial Venues: ORP and NAD+ reduction analyses.
The study finds out from its analysis that silica hydride demonstrates the compound as a significant reducing agent and potential energy source. “From the biological standpoint, the silica hydride compound has considerable additional properties, as a reducing agent for free radicals in the body and as an internal, cellular fuel cell.” Tests results “indicate no induced cellular toxicity from the silica hydride or the resultant increased NADH concentration. Combinatorially, the low ORP, reduced rH, and ability to consistently reduce NAD provide a solid basis for further investigation into this hydride family as an alternate hydrogen mechanism in biological and industrial arenas.”
Journal of Medicinal Food, Volume 7, Issue Number 1, 2004. Differential Metabolic Effects on Mitochondria by Silica Hydride Using Capillary Electrophoresis.
“The results of this assay indicate an increase in metabolic rate and internal cellular energy production relative to the nontreated system.” “In the mitochondrial samples, the ratio of NADH/NAD increased twofold, the ATP increased fivefold and glucose levels decreased twofold.
” A controlled clinical trial showed that in eight normal adult subjects, seven of the nine Biological Terrain Assessment parameters improved. Saliva pH, saliva rH2, blood resistivity, and urine resistivity showed statistically significant improvement (p >0.05) for these eight subjects after 18 days of supplementation with 4 Microhydrin (now known as Active H-) capsules per day on a schedule of one in the morning, two at midday and one in the evening. Three other parameters (urine pH, urine rH2, and saliva resistivity) also showed improvement over the 18-day supplementation period when their averaged changes were calculated. Blood pH and blood rH2 were the only parameters that did not change during the supplementation period. These values may not change as readily due to the heterogenous and stable nature of blood. The nutritionists and physicians who monitored the study with Biological Terrain Assessment results and other clinical data observed no adverse side effects in this group during the supplementation period. Presented at the American College of Nutrition Symposium on Advances in Clinical Nutrition. Albuquerque, New Mexico, October, 1998.
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